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Key Features * Provides a detailed review of the unique challenges
presented by young patients with small heart size, and patients of
any age with distorted anatomy due to congenital heart disease, in
this long overdue, updated text. * Intends to guide all
cardiologists engaged in invasive electrophysiology at both the
training level and established practice who are exposed to such
exceptional cases. * Includes an internationally recognized group
of experts who discuss the technical approach, success rate,
complication rate, and special precautions needed to achieve
optimal outcomes.
Key Features * Provides a detailed review of the unique challenges
presented by young patients with small heart size, and patients of
any age with distorted anatomy due to congenital heart disease, in
this long overdue, updated text. * Intends to guide all
cardiologists engaged in invasive electrophysiology at both the
training level and established practice who are exposed to such
exceptional cases. * Includes an internationally recognized group
of experts who discuss the technical approach, success rate,
complication rate, and special precautions needed to achieve
optimal outcomes.
This issue of Cardiac Electrophysiology Clinics, Guest Edited by
Drs. Mohammad Shenasa, Prashanthan Sanders, and Stanley Nattel, is
dedicated to Risk Factors in Atrial Fibrillation: Appraisal of AF
Risk Stratification. This is one of four issues selected each year
by the series Consulting Editors, Ranjan K. Thakur and Andrea
Natale. Topics include, but are not limited to, Epidemiology of
Atrial Fibrillation; Hypertension, Prehypertension, Hypertensive
Heart Disease and Atrial Fibrillation; Pulmonary Disease, Pulmonary
Hypertension and Atrial Fibrillation; Heart Failure with Preserved
(HFpEF) and Reduced (HFrEF) LV Systolic Function, Diastolic
Dysfunction; Coronary Artery Disease; ECG and Echo Abnormalities in
Patients with Atrial Fibrillation Risk Factors; Diabetes and
Endocrine Disorders; Obesity and Metabolic Syndrome in Atrial
Fibrillation; Renal Disease; Sleep Apnea and Atrial Fibrillation;
Channelopathies in Atrial Fibrillation; Implications of
Inflammation and Myocardial Fibrosis in Atrial Fibrillation; Role
of Biomarkers in Atrial Fibrillation; Left Ventricular Hypertrophy
and Other Cardiomyopathies in Atrial Fibrillation; Atrial
Fibrillation in Valvular Heart Disease; Atrial Fibrillation in
Adult Congenital Heart Disease; Exercise and Athletic Activity in
Atrial Fibrillation; Post-op Atrial Fibrillation; Autonomic
Dysfunction and Neurohormonal Disorders in Atrial Fibrillation;
Social Risk Factors; Atrial Fibrillation and Stroke; Screening for
Atrial Fibrillation Risk Factors; Primary Care and Internists
Perspective on Atrial Fibrillation Risk Factors; and Lifestyle as a
Risk Factor for Atrial Fibrillation.
This issue of Cardiac Electrophysiology Clinics, guest edited by
Mohammad Shenasa and Amin Al-Ahmad, is the second part of our
Advances in Cardiac Mapping and Catheter Ablation issue. Article
topics will include, but are not limited to, New Findings in Atrial
Fibrillation Mechanisms; Mapping and Ablation of Neuraxial in
Patients with Ventricular Arrhythmias; How to Map and Ablate Rotors
in Atrial Fibrillation; Post-ablation Atrial Arrhythmias; Substrate
Mapping in Atrial Arrhythmias; Substrate Mapping in Ventricular
Arrhythmias; Challenges in Ablation of Complex Congenital Heart
Disease; Mapping and Ablation of Ventricular Arrhythmias from the
RV and LV Outflow Tract; Novel Insights on Idiopathic VF and Early
Repolarization; Novel Observations in Mapping and Ablation in
Brugada Syndrome; Ablations of Ventricular Arrhythmias; Mapping and
Ablation of Arrhythmias from uncommon sites; Mapping and Ablation
of VT in Patients with HF and Cardiomyopathies; Mapping and
Ablation of Unmappable VT, VT Storm, and Those in Acute Myocardial
Infarction; Mapping and Ablation of Ventricle Arrhythmia in
patients of LVAD; Fluoroless Catheter Ablation of Cardiac
Arrhythmias; Toward a Uniform Ablation Protocol for Paroxysmal;
Persistent and Permanent AF; and The Ideal Mapping System.
This issue of Cardiac Electrophysiology Clinics, edited by Drs.
Mohammad Shenasa, N. A. Mark Estes III, and Gordon F. Tomaselli,
will cover Contemporary Challenges in Sudden Cardiac Death. Topics
covered in this issue include Pathophysiology; Basic
electrophysiological mechanism; Channelopathy and Myopathy as
causes of sudden cardiac death; Public access to defibrillation;
Sudden cardiac death in children adolescence; Sudden cardiac death
in specific cardiomyopathies; Ventricular arrhythmias and sudden
cardiac death; lessons learned from cardiac implantable rhythm
devices; future directions, and more.
This issue of Cardiac Electrophysiology Clinics examines
Arrhythmias in Cardiomyopathies. Articles include Atrial and
Ventricular Arrhythmias in Hypertrophic Cardiomyopathy and Its
Variants; Role of Cardiac MRI in Risk Stratification of
Hypertrophic Cardiomyopathy; Arrhythmogenic Right Ventricular
Dysplasia/Cardiomyopathy; Exercise-Induced Right Ventricular
Cardiomyopathy; Dilated Cardiomyopathy; Sarcoidosis; Amyloidosis;
Chagas Disease; Fabry Disease; Left Ventricular Hypertrophy:
Ventricular Arrhythmias and SCD; Left Ventricular Non-compaction;
Mitochondrial Cardiomyopathy and Related Arrhythmias; Arrhythmias
in Viral Myocarditis and Pericarditis Cardiomyopathy; Takotsubo
Cardiomyopathy; Post-partum Cardiomyopathy; Arrhythmias in Alcohol-
and Drug-Associated Cardiomyopathies; Arrhythmias in Neuromuscular
Dystrophies; Cardiomyopathies Related to Anti-cancer Therapy- and
Radiation- Induced Heart Disease; Arrhythmias After Myocardial Stem
Cell Therapy; and more.
This issue of Cardiac Electrophysiology Clinics examines
electrocardiography of complex arrhythmias. Topics include
concealed conduction, right and left atrial macroreentrant
tachycardias, focal atrial fachycardias, AV nodal and AV reentrant
tachycardia, wide complex tachycardias, ventricular tachycardia in
CAD, ECG characteristics of outflow tract VT, fascicular
tachycardias, VT in non-ischemic dilated cardiomyopathy, VT
originating from unusual sites, incessant VT and VT storms, ECG
characteristics of TdP, VT in ARVC, and ventricular arrhythmia in
inherited channelopathies, arrrhythmias in complex congenital heart
disease, AV conduction disease and block, electrocardiographic
analysis of paced rhythms.
This issue of Cardiac Electrophysiology Clinics, edited by Drs.
Mohammad Shenasa and Stanley Nattel, will review Cardiac Potassium
Channel Disorders in depth. Topics covered include but are not
limited to: Molecular Biology of Cardiac Potassium Channels;
Genetic Control of Potassium Channels; Potassium Channel Remodeling
in Heart Disease; Gender-specific Effects of Potassium Channel
Blockers; Pharmacogenetics of Potassium Channel Blockers;
Multichannel Blockers; Selective Potassium Channel Blockers; and
Proarrhythmic and Torsadogenic Effects of Potassium Channel
Blockers in Patients.
This issue of Cardiac Electrophysiology Clinics, guest edited by
Mohammad Shenasa and Amin Al-Ahmad, will focus on Advances in
Cardiac Mapping and Catheter Ablation. This is part one of a
two-part issue and will include articles centered around Basic
Concepts in Cardiac Mapping, Novel Mapping & Imaging Systems
& Technologies, and Catheter and Energy Sources. Topics
include, but are not limited to, Embryology of the Cardiac
Conduction System Relevant to Cardiac Arrhythmias; Anatomical
Consideration Relevant to Atrial and Ventricular Arrhythmias;
Fundamentals of Cardiac Mapping; Novel Cardiac Mapping Systems;
Non-invasive Mapping & ECGI in Atrial and Ventricular
Arrhythmias; Optical Mapping; Omnipolar Mapping; Cardiac CT, MRI,
and Fibrosis Quantification; High resolution mapping in patients
with atrial and ventricular arrhythmias; Contact Force and Ablation
Index; and New Catheter Balloons Including Radiofrequency.
The past 10 years have seen a remarkable change in the approach to
cardiac arrhythmias, from a position of confidence and a feeling of
well-being about pharmacological treatment to a situation in which
there is now marked uncertainty and general apprehension about the
role of antiarrhythmic drugs. Until relatively recently the
prevailing concept in antiarrhythmic therapy was that arrhythmias
could be controlled by drugs which slowed conduction or suppressed
automaticity, goals well served by the sodium channel-blocking
drugs and glycosides. Drug re search was based largely on the
development of agents mimicking those already available, but with
greater efficacy, fewer side effects or a more favourable phar
macokinetic profile. The CAST trial stands out as a landmark in the
evolution of arrhytmia manage ment; rarely has a single trial had
such a profound impact not only on clinical prac tice, but also on
the whole approach of those involved in the research, development
and regulation of antiarrhythmic drugs. The results of the CAST
trial, designed to redress the shortcomings of earlier trials which
had failed to demonstrate the anticipated improvement in mortality
post-myocardial infarction with the use of class I agents, are well
known. The CAST and CAST II showed an increase in mor tality
associated with the active agent (encainide, flecainide or
morizicine) com pared to placebo treatment. They firmly established
the potential danger in the use of class I drugs."
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